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Právě je čtvrtek, 20.září 2018, 19:37 hod.
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WEP-M+2 2018-09-19 12:52:21
12-digit factor of P2203 has now been found by the project... Nové okno
...158848 times

 
Rosetta 2018-09-18 01:14:21
Fluorescent proteins designed from scratch Nové okno


Congrats to all Rosetta@home volunteers who contributed to a recent report in Nature describing the design of a completely artificial fluorescent beta-barrel protein. As described by one of the main authors, Anastassia, in this forum post:

The paper presents many “firsts” in computational protein design. It is the first de novo design of the beta-barrel fold (one of the most described folds in the past 35 years, yet mysterious until now). It is also the first de novo design of a protein tailored to bind a small-molecule, which requires very high accuracy in the placement of side chains on protein backbones assembled from scratch. Additionally, we could show that these new proteins could fold and function as expected in vivo! We hope that the advances described in the paper will further enable the de novo design of many biosensors and catalysts tailored for specific applications.

Thanks to all the Rosetta@home volunteers who contributed to the validation of our designed proteins and binding sites.

Here is the link to the IPD webpage that contains a copy of the paper. The work was also featured in the news articles below (the news in Science contains a video of one of our proteins glowing in living cells).

https://www.bakerlab.org/index.php/2018/09/12/de-novo-fluorescent-proteins

https://cen.acs.org/physical-chemistry/periodic-table/Designer-protein-tackles-binding/96/i37
http://www.sciencemag.org/news/2018/09/watch-these-new-designer-proteins-light-when-they-hit-their-target

 
CSG 2018-09-17 09:10:33
[all] status update Nové okno
Hi Everyone!

Sorry for a lot of silence on our end -- things have been quite hectic this summer! I accepted a new position and now am at Rochester Institute of Technology and busily getting a new lab set up (and having some students migrate along with me).

I'm going to let some of the work units clear out of the system and set up some new runs which should help fix some of the issues you've been seeing with bad workunits. In the longer term, I've started work on an updated binary which should also allow for the use of GPUs, which should hopefully allow the runs to scale a bit better without running into these problems.

I'll be keeping you posted as that comes along, but right now we're all just trying to get settled in a new place! Thanks again for all your support. The results coming in are definitely interesting ones!


I don't see anything wrong the the tasks. [b]JUST BAD HOSTS!!! [/b]Please ban them. So, so many bad hosts. Easily at least every other task seems to have an error on it from some 'Anonymous' user that we all know is Gridcoin.
https://csgrid.org/csg/forum_thread.php?id=2534

Are the tasks currently in progress going to be uploaded? Right now they are just stuck and it seems like they are just going to be abandoned based off your comment.


Congratulations Travis! Go Tigers! :^)

@mmonnin I posted some info on bad hosts here:

https://csgrid.org/csg/forum_thread.php?id=2534

 
Acoustics 2018-09-15 23:38:08
Report at GRID'2018 Nové okno
The report 'Application of BOINC-based volunteer computing for comparison of the geoacoustic inversion algorithms efficiency.' was made in Dubna at the conference GRID'2018. In this report, results obtained in Acoustics@home are discussed. The presentation is available online

На 8-ой международной конференции GRID'2018 в Дубне был сделан доклад по результатам Acoustics@home.

 
XANSONS 2018-09-15 20:30:53
467 new structures Nové okno
New COD entries are added.

Update. All WUs are sent to the hosts.

 
PrimeGrid 2018-09-15 13:03:13
Oktoberfest Challenge! Nové okno
From September 15th, 2018 Primegrid will be running a Cullen Challenge to celebrate Oktoberfest! The wold's biggest Volkfest is held annually in Munich, Bavaria, Germany, with more than six million people from around the world attending. The 7 day Challenge starts at 18:00 UTC and ends on 22nd September exactly one week later at 18:00 UTC. Work units from the CUL (LLR) project, which are downloaded and completed during the challenge will count towards your challenge score. The last Cullen Prime found was 6679881*2^6679881+1 from 2009. We're now testing numbers past 16M, so emotionally due for a prime. For more information and discussion, please head over to the official challenge thread: http://www.primegrid.com/forum_thread.php?id=8194 Good luck!

 
RakeSearch 2018-09-15 11:55:10
Cep and first half of September 2018! Nové okno
Dear participants!

Long summer days are left behind, solemn autumn comes! Clouds are more and more often close the Sun, and before goes to winter sleep, using a leafs, berries, mushrooms, water, bark and needles, nature turns Karelian forests into majestic picture, painting them with all colors of the rainbow. Cep may be one of best symbols of this time! And like lucky mushroomer, participants of our project find a many results with ODLS pairs - 2408 in first half of month! The most fortunate were 152 of them:

LCB001 (Hardware Canucks) and forest (Czech National Team),
SerGiani (Russia Team) and Bryan (SETI.USA),
jondi_hanluc (OcUK - Overclockers UK) and cbc22,
meadoel (BOINCstats) and vanos0512 (BOINC@Taiwan),
[B@P] Daniel (BOINC@Poland) and whizbang (Ars Technica),
okuzonosb (Team China) and Sphynx (SETI.USA),
PDW (OcUK - Overclockers UK) and BEKO (Czech National Team),
Dmitriy Otroschenko (Ukraine) and necavi (BOINC@Poland),
BritishBob (Overclock.net) and Beyond (Ars Technica),
[AF>Libristes]cguillem (L'Alliance Francophone) and fsclavo,
conf [MM] (SETI.USA) and Steve Dodd (The Planetary Society),
owensse (The Planetary Society) and Tom Poleski (BOINC@Poland),
whowhere (AUGE@BOINC) and ShmyaCluster (Crystal Dream),
Ralfy (BOINC Confederation) and Gibson Praise (Picard),
[AF>Belgique]Mamouth (L'Alliance Francophone) and Vitalii Koshura,
[SG] blAckmAmbA (SETI.Germany) and Landjunge (Planet 3DNow!),
[AF>Amis des Lapins] Xe120 (L'Alliance Francophone) and tehhustler,
[AF>Libristes]MortelKni (L'Alliance Francophone) and Sengieffe,
glennpat (XtremeSystems) and Clank [MM] (SETI.USA),
kashi (BOINC@AUSTRALIA) and Yi-Ming Wang (Team China),
OldChap (XtremeSystems) and hoarfrost (Crystal Dream),
[AF>Amis des Lapins] Nabz37 (L'Alliance Francophone) and Millenium,
Thyler Durden@P3D (Planet 3DNow!) and EG (SETI.USA),
HenkM (Dutch Power Cows) and Howdy2u2 (TeAm AnandTech),
KWSN-SpongeBob SquarePants (The Knights Who Say Ni!) and adams,
[AF>Amis des Lapins] Ceclo (L'Alliance Francophone) and rebel9,
JonS (UK BOINC Team) and Conan (Cobar Spiders),
KPX (Czech National Team) and herby44 (Planet 3DNow!),
stoneageman (XtremeSystems) and GLeeM (TeAm AnandTech),
[AF>Amis des Lapins] Phil1966 (L'Alliance Francophone) and arkiss,
JagDoc (Planet 3DNow!) and Shmya-2 (Crystal Dream),
hoppisaur (Ars Technica) and morgan (Team Norway),
Mumps [MM] (SETI.USA) and firstomega (Rechenkraft.net),
VietOZ (XtremeSystems) and Pjotr Panski (SETI.Germany),
bluestang (XtremeSystems) and robbysites (Crunching@EVGA),
europe64 (europe64) and Michael H.W. Weber (Rechenkraft.net),
Gipsel (Planet 3DNow!) and purplecfh (SETI.USA),
ReaDy (Astronomy.Ru Forum) and jozef j (Russia Team),
http://vk.com/boinc (Karelia) and cc-smokey (CC-Team),
Kodeks IT (Karelia) and Casey ([H]ardOCP),
[DPC]Blah.NET (Dutch Power Cows) and lydy1993 (Team China),
Rhodan71 (L'Alliance Francophone) and saiz (Team China),
jiri kovar (LITOMYSL Boinc Team Czech Republic) and Grandpa Tom,
cineon_lut [BlackOps] (SETI.USA) and Astronomy.Karelia (Karelia),
eLPeCKo (Czech National Team) and Птицы Петрозаводска (Karelia),
Shaman (Czech National Team) and citerra (Russia Team),
[SG-FC]shka (SETI.Germany) and zzuupp (TeAm AnandTech),
bcavnaugh (Crunching@EVGA) and JohnMD (BOINC@Denmark),
Международная база наблюдений комет (Karelia) and MatzeKnop,
nenym (Czech National Team) and respawner (Rechenkraft.net),
Kalomel (BOINC@Poland) and HK-Steve (Crunching@EVGA),
freestman (Chinese Dream) and Daniel (BOINC@AUSTRALIA),
Karelian Center for Gender Studies (Karelia) and Hartmut 53,
Johannes Elsner (Planet 3DNow!) and Maxwell [MM] (SETI.USA),
[AF] Skinny06 (L'Alliance Francophone) and Andreas64,
Vincent Dark (Team China) and Crunch3r (BOINC United),
ankyungha (SETIKAH@KOREA) and CoolAtchOk (Russia Team),
BlackGoose05 (Team Biss!) and Jerzy_Przytocki (BOINC@Poland),
Dingo (BOINC@AUSTRALIA) and joe carnivore (Planet 3DNow!),
declis (Rechenkraft.net) and KR Center (Karelia),
BlisteringSheep (Ars Technica) and ext2097 (SETIKAH@KOREA),
Bill F (Worldwide TechServices) and MindCrime (SETI.USA),
MajkPascal (BOINC@Poland) and Sergey Zhikhorev (Russia Team),
RFGuy_KCCO ([H]ardOCP) and cluster-krc (Karelia),
mimeq (BOINC@Poland) and [SG-2W]Kurzer (SETI.Germany),
Miroslav Splichal (LITOMYSL Boinc Team Czech Republic) and Uli2*,
Henk Haneveld (Dutch Power Cows) and Lycidas (BOINC@Heidelberg),
the-who (Team China) and Odd-Rod (BOINCstats),
amazing (SETIKAH@KOREA) and LeChat51X (L'Alliance Francophone),
entigy (Team England (Boinc)) and mmonnin (Overclock.net),
Skywalker@Athens (Macedonia is Greek!) and sergamena (Russia Team),
Pavel_Kirpichenko (Astronomy.Ru Forum) and [SG] Felix (SETI.Germany),
k4m1k4z3 (Overclock.net) and Theadalus (Dutch Power Cows),
Indy (Czech National Team) and Skivelitis2 (Overclock.net),
Adam J Bavier ([H]ardOCP) and Kwartet! (Dutch Power Cows),
EarlyBird@Zircons (BOINC@Taiwan) and Argento (BOINC@Poland).

Thank you for attention to RakeSearch project and participation! From beginning of month 2.3% of whole workunits set were processed!

 
GoofyxGrid NCI 2018-09-12 07:33:11
URGENT: Accident in workplace Nové okno
Last night an accident occurred in my office.
A water pipe burst in the wall which resulted in damage to the wall and flooding of the entire office. Fortunately, nothing happened to the main servers <- I have a few other losses that I need to complete.

Unfortunately, this means that today I am forced to turn off and bring all equipment to a safe place to repair the pipe and wall.

I plan to return to the office on Friday or Saturday.
I apologize for this break and I am asking everyone for your understanding.

I will back to you crunchers

 
GoofyxGrid CPU 2018-09-12 07:33:08
URGENT: Accident in workplace Nové okno
Last night an accident occurred in my office.
A water pipe burst in the wall which resulted in damage to the wall and flooding of the entire office. Fortunately, nothing happened to the main servers <- I have a few other losses that I need to complete.

Unfortunately, this means that today I am forced to turn off and bring all equipment to a safe place to repair the pipe and wall.

I plan to return to the office on Friday or Saturday.
I apologize for this break and I am asking everyone for your understanding.

I will back to you crunchers

 
NumberFields 2018-09-09 17:15:41
Septic App Complete Nové okno
The septic app is now officially complete. The final tally of results are as follows:
    Inspected 38136713961009 polynomials.
    # Polys passing field disc test = 36163948.
    # Polys after refinement = 1009140.
    Elapsed Time (summed over all clients) = 3.31043e+07 hours



The key piece of information here is that there are 1,009,140 septic fields with discriminant less than 200E6. We have these fields available as a text file to anyone who might be interested. They will also be added to the numberfields database:
https://hobbes.la.asu.edu/NFDB/

We plan on submitting these results (with a more detailed discussion) in the form of a journal article. I will report back here with details of that as I get more information.


 
SRBase 2018-09-08 09:51:20
Looking for a compiler Nové okno
I have planned a long time ago a new subproject with opencl but cannot compile it with visual studio. If you are able to compile it under windows, linux and mac let me know. The source code can be found here.

I also need to find out how the app is running with which commands.

 
Leiden Classical 2018-09-06 00:00:00
Project News 6 sept 2018 Nové okno
The server will be taken off line before the end of november 2018.

 
YAFU 2018-09-05 19:14:11
Aliquot sequence 1592796 has terminated!!! Nové okno
Aliquot sequence 1592796 has terminated!!!


 
MilkyWay 2018-09-04 19:08:03
Database Maintenance 9-4-2014 Nové okno
We are updating the database currently. The server will be down.
As of 1:30 pm EST.

 
XANSONS 2018-09-01 21:01:34
439 new structures Nové okno
New COD entries are added.

Update. All WUs are sent to the hosts.

 
RakeSearch 2018-09-01 18:48:40
August 2018 totals! Nové okno
Dear participants!

After post-sprint relaxation in the first half of month, the spirit of it returned again! Amazing view of Spa-Francorchamps is already behind but the sky of Monza with the Ferrari flags is ahead. Totally 3438 results with "permutational" ODLS pairs were found in August and 2004 - in the second half! This was done by 137 participants:

CoolAtchOk (Russia Team) and Gipsel (Planet 3DNow!),
eisler jiri (Czech National Team) and Hartmut 53,
vanos0512 (BOINC@Taiwan) and Ralfy (BOINC Confederation),
Pete Broad (BOINC Synergy) and Dmitriy Otroschenko (Ukraine),
morgan (Team Norway) and Theadalus (Dutch Power Cows),
cineon_lut [BlackOps] (SETI.USA) and the-who (Team China),
Steve Dodd (The Planetary Society) and herby44 (Planet 3DNow!),
Natalia (Crystal Dream) and hoarfrost (Crystal Dream),
[AF>Libristes]MortelKni (L'Alliance Francophone) and arkiss,
saiz (Team China) and Landjunge (Planet 3DNow!),
Beyond (Ars Technica) and SergOZ (Crystal Dream),
KWSN-SpongeBob SquarePants (The Knights Who Say Ni!) and fix
PDW (OcUK - Overclockers UK) and JagDoc (Planet 3DNow!),
Thyler Durden@P3D (Planet 3DNow!) and gingavasalata (Hrvatska),
EG (SETI.USA) and Chipotle (Ars Technica),
HenkM (Dutch Power Cows) and forest (Czech National Team),
[DPC]Blah.NET (Dutch Power Cows) and LCB001 (Hardware Canucks),
Soderstromm (Gridcoin) and [B@P] Daniel (BOINC@Poland),
Yi-Ming Wang (Team China) and purplecfh (SETI.USA),
jozef j (Russia Team) and Adam J Bavier ([H]ardOCP),
Mumps [MM] (SETI.USA) and Howdy2u2 (TeAm AnandTech),
Rob ([H]ardOCP) and Shmya-2 (Crystal Dream),
polarbeardj (Crunching@EVGA) and http://vk.com/boinc (Karelia),
nabializm (BOINC@Poland) and Alez (The Scottish Boinc Team),
nenym (Czech National Team) and GLeeM (TeAm AnandTech),
[SG-FC]shka (SETI.Germany) and Martin Droppa,
Casey ([H]ardOCP) and lydy1993 (Team China),
KPX (Czech National Team) and firstomega (Rechenkraft.net),
[AF>Amis des Lapins] Xe120 (L'Alliance Francophone) and cbc22,
Stimpy (Rechenkraft.net) and eLPeCKo (Czech National Team),
BlisteringSheep (Ars Technica) and Crunch3r (BOINC United),
Gibson Praise (Picard) and ReaDy (Astronomy.Ru Forum)
[AF>Amis des Lapins] Phil1966 (L'Alliance Francophone) and fsclavo,
robbysites (Crunching@EVGA) and runs2far ([H]ardOCP),
bcavnaugh (Crunching@EVGA) and Kwartet! (Dutch Power Cows),
declis (Rechenkraft.net) and Wabi CZ (Czech National Team),
WyerByter (Gridcoin) and JonS (UK BOINC Team),
ext2097 (SETIKAH@KOREA) and Millenium,
ChristianVirtual ([H]ardOCP) and Sengieffe,
Oleg (Russia Team) and ShmyaCluster (Crystal Dream),
okuzonosb (Team China) and Conan (Cobar Spiders),
Clank [MM] (SETI.USA) and Dirk Broer (AMD Users),
[AF>EDLS] Jakez Sulli (L'Alliance Francophone) and Vitalii Koshura,
Jeff17 (BOINCstats) and JohnMD (BOINC@Denmark),
necavi (BOINC@Poland) and BlackGoose05 (Team Biss!),
Kalomel (BOINC@Poland) and MindCrime (SETI.USA),
[AF>Libristes]cguillem (L'Alliance Francophone) and Progger,
BEKO (Czech National Team) and =Lupus= (BOINC Confederation),
Bruce Kennedy (BOINCstats) and KR Center (Karelia),
whizbang (Ars Technica) and sergamena (Russia Team),
BritishBob (Overclock.net) and zzuupp (TeAm AnandTech),
modesti (L'Alliance Francophone) and Astronomy.Karelia (Karelia),
cc-smokey (CC-Team) and NOSTROMUS (Catalunya),
europe64 (europe64) and Vincent Dark (Team China),
hoppisaur (Ars Technica) and k4m1k4z3 (Overclock.net),
Sergey Zhikhorev (Russia Team) and User (Karelia),
citerra (Russia Team) and entigy (Team England[/b] (Boinc)),
Karelian Center for Gender Studies (Karelia) and FDB ITALIA S.r.l.,
Gusek (Russia Team) and VietOZ (XtremeSystems),
Международная база наблюдений комет (Karelia) and Robert,
Werinbert (Free-DC) and conf [MM] (SETI.USA),
Nightmare (XtremeSystems) and [SG] Felix (SETI.Germany),
Michael H.W. Weber (Rechenkraft.net) and Luigi R. (BOINC.Italy),
Johannes Elsner (Planet 3DNow!) and Sphynx (SETI.USA),
jondi_hanluc (OcUK - Overclockers UK) and bluestang (XtremeSystems),
[AF] Skinny06 (L'Alliance Francophone) and glennpat (XtremeSystems),
Pavel_Kirpichenko (Astronomy.Ru Forum) and Derivator (SETI.Germany),
ankyungha (SETIKAH@KOREA) and whowhere (AUGE@BOINC),
fax (Meisterkuehler.de Team).

Thank you for attention to the project and we wish you an exсiting translation from Grand Prix race in Monza!

 
SRBase 2018-08-31 18:47:51
base R873 Megaprime Nové okno
And again, on 22th of August, Deltik, a member of the team Gridcoin has found a megaprime 104*873^344135-1 for base R873. The prime has 1.012.108 digits and entered the TOP5000 in Chris Caldwell's The Largest Known Primes Database.

Well done!

 
MilkyWay 2018-08-30 19:34:41
Database Maintenance Nové okno
Hello Everyone.
I am Jeff Thompson and have been working on and off with MilkyWay@home since 2012, but I have been quiet recently.

For the next few months, on Tuesdays, we will be scheduling server maintenance.
We will post on the day threads for any issues that may arise.

This is a heads up.

Thank you for your continued support.

 
YAFU 2018-08-29 20:08:10
Aliquot sequence 1404060 has terminated!!! Nové okno
Aliquot sequence 1404060 has terminated!!!


 
SRBase 2018-08-28 19:47:02
base R978 Megaprime Nové okno
On 19th of August, Deltik, a member of the team Gridcoin has found a megaprime 164*978^387920-1 for base R978. The prime has 1.160.015 digits and entered the TOP5000 in Chris Caldwell's The Largest Known Primes Database.

Well done!


 Další

Thanks to David Vignoni for graphics and inspiration.


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